Who is the Bio Propolis defense APF® 10 spray intended for?

  • All those who are looking for quick and efficient help with sore throat and pharynx
  • Adults (also pregnant women and breastfeeding mothers), teenagers and children from the age of 3 onwards
  • All those who are looking for alcohol-free propolis which does not irritate the mucosa
  • All those who prefer propolis without artificial additives
  • All those who want to use propolis, verified by clinical studies
  • All those who value this natural wonder which has been protecting bees against microbes for millions of years

Quick facts about the Bio Propolis def. APF® 10 spray

Water-based Propolis defense does not contain alcohol, it is therefore recommended, in addition to the general adult population, to pregnant women, breastfeeding mothers, teenagers and children from the age of 3 onwards.
The BIO label means that the ingredients used in the product are organically produced.
The APF® 10 factor (Active Propolis Flavonoids) means that the flavonoid concen. in a product is a min. of 10 mg/ml, with which the high quality and repeatable effect of the product may be guaranteed.
The recommended daily dose for adults is 6-times 3 applications per day, and for children from 3 to 12 years of age the dose is 5-times 2 applications per day directly into the oral cavity.
This means that the raw material itself was standardised, followed by an additional standardisation of the end product. The recommended daily doses are adapted to clinical study findings.
The product is 100% natural with organically produced ingredients and without preservatives as well as other artificial additives.
About product

The strongest oral spray with water-based propolis

The Propolis defense APF® 10 oral spray is the strongest water-based propolis spray on the market. It does not contain alcohol, does not irritate the mucosa and does not stain tooth enamel. It also has an excellent taste, since it contains honey and peppermint essential oil. It may also be used by those who cannot enjoy alcohol or avoid it – children from the age of 3 onwards, teenagers, pregnant women and breastfeeding mothers.

The spray is convenient to use, since it is always at hand or you may keep it in your bag – for regular use in the oral cavity. Propolis, which with its antibacterial, antiviral and antifungal action has been protecting bees from infections for millions of years, was used by people even before the Christian Era and is still one of the most verified and popular medicines in medicine cabinets.


Why is the Bio Propolis defense APF® 10 spray so efficient?

The Bio Propolis defense APF® 10 oral spray contains organically produced, double standardised propolis (standard raw material and end product) with the APF® 10 factor. The APF® factor (Active Propolis Flavonoids) determines the concentration of flavonoids in the product, which ensures high quality and repeatable effect of the product. The concentration of flavonoids in propolis is a minimum of 10 mg/ml, and the recommended daily doses are adjusted to the results of clinical studies.

The product is 100% natural with organically produced ingredients and without preservatives, propylene glycol and polyethylene glycol. Due to added honey and peppermint essential oil it has an excellent taste, does not irritate the mucosa and does not burn.

More Information
Značka najbolje prodajanoNo
PodnaslovDietary supplement;spray;bottle 30 ml;30 days of regular use
PropertiesNo artificial colours, Natural, No artificial flavorings, Gluten free, No preservatives
Uporaba izdelkov
Recommended daily amount and dosage instructions:

Način uporabe:

The recommended daily dose for adults and teenagers over 12 years of age is 6-times 3 applications directly into the oral cavity.

The recommended daily dose for children over 3 years of age is 5-times 2 applications directly into the oral cavity.

Spray directly into the oral cavity. Shake well before use.


Liquid propolis extract* (emulsifier: vegetable glycerol*, propolis extract*, water, brown sugar*, thickener: gum arabic*, maltodextrine*, colourant: caramel*), purified water, honey* 10%, peppermint essential oil* (Mentha piperita), natural flavouring*- * organically produced.

Propolis flavonoids

22 mg

Customer Questions
What is propolis?
Propolis or bee glue is a bee product that is necessary in order to keep the beehive healthy. It contains a mixture of natural resins gathered by bees on tree buds, enriched by secretions from their glands with the addition of beeswax. The sticky mixture is needed for repairing the honeycombs and coating the internal walls of the beehive, thereby preventing moisture and wind from penetrating and protecting the beehive against microbes. Bees also use it to embalm larger intruders that cannot be otherwise disposed of. In this way they prevent their degradation and thus protect themselves against infections and diseases.
Why is Propolis defense the strongest on the market?
The Propolis defense line boasts the highest concentration of propolis bioflavonoids. APF = Active Propolis Flavonoids is a standardised scheme developed by Medex and implemented in our own laboratories with recognised analysis methods. It enables us to maintain an unchanged concentration of propolis flavonoids in the product, regardless of the batch and fluctuations in natural components. The strength and quality of products in the Propolis defense line is standardised with the APF® factor (Active Propolis Flavonoids), which specifies the flavonoid concentration in a products, and daily doses are adjusted to findings of clinical studies. APF® 10 therefore means, for example, that the flavonoid concentration in a product is a minimum of 10 mg/ml, with which the high quality and repeatable effect of our products may be guaranteed.
Is every propolis equally effective?
Propolis consists of over three hundred compounds, of which flavonoids are the most important. The quantity of flavonoids in propolis largely depends on the season and the location where bees are collecting pollen. If you wish to make use of the beneficial effects of propolis which have been confirmed through clinical research, you have to opt for a propolis with a guaranteed flavonoid content and stick to equal daily doses. Data on propolis concentration, expressed in percentages, as we often see on propolis packaging, do not tell us anything about flavonoid content, and are therefore not indicative of the efficiency of propolis. Here at Medex, we only use standardised propolis (standardised ingredients and end products) indicated by the so-called APF® (Active Propolis Flavonoids) factor.
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Why choose Medex?


A bee family is an extraordinary superorganism. Each member has a specific role, which has preserved this species for millions of years. Bees, these amazing beings, “invented” magnificent preparations, such as propolis, royal jelly, honey, bee pollen – which are beneficial for people as well –, in order to survive. A Slovenian saying goes: Follow the bees. This is also the genetic make-up of our company, which defines us and from which we draw inspiration for our work.

Tradition and the power of nature remain the source and inspiration for our work. We complement them with the verified quality of patented and standardised ingredients, the effects of which are proven by clinical studies, in the right doses and combinations. In Medex’s development laboratories a registered research team with 4 PhDs develops products that combine traditional use with clinically proven effects.

Medex products are based on standardised and controlled content of main active substances and high production standards with which we ensure their consistent quality. We also pay significant attention to selecting packaging and have been packing an increasing number of products in glass packaging in order to preserve the value and efficiency of natural active substances as best as possible and at the same to take better care for the environment.

Medex has been operating in a sustainable manner for decades. From a company, which established and developed beekeeping already in former Yugoslavia, grew an undertaking that is expanding beekeeping around the world. In this manner we are realising quite a few of the seventeen of Unesco’s sustainable goals: eliminating poverty, hunger, caring of the environment, empowering women. Indeed, beekeeping contributes to the achievement of all these goals.

Dietary supplement spray bottle 30 ml 30 days of regular use
  • The strongest spray with standardised water-based propolis on the market
  • Does not irritate the mucosa and does not stain tooth enamel
  • Also suitable for pregnant , breastfeeding women and children 3+
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